Thalidomide

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History

The Development

1946

Hermann Wirtz founded Chemie Grünenthal GmbH

1947

Registration of Penicillin

1957

Launch of Thalidomide (withdrawn from market in 1961)

1968

First international activities

1977

Tramal® launched – worldwide partnering

since 2000

Global launches (Zaldiar®, Transtec®)

since 2004

Broad investments in R&D and late clinical trials

2008

Approval of Tapentadol in the US

2009

EU submission of Tapentadol for acute and chronic pain, launch of Nucynta® in the US by Johnson & Johnson